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Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions
Glucose is vital for life, serving as both a source of energy and carbon building block for growth. When glucose is limiting, alternative nutrients must be harnessed. To identify mechanisms by which cells can tolerate complete loss of glucose, we performed nutrient-sensitized genome-wide genetic scr...
Autores principales: | Skinner, Owen S., Blanco-Fernández, Joan, Goodman, Russell P., Kawakami, Akinori, Shen, Hongying, Kemény, Lajos V., Joesch-Cohen, Lena, Rees, Matthew G., Roth, Jennifer A., Fisher, David E., Mootha, Vamsi K., Jourdain, Alexis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229423/ https://www.ncbi.nlm.nih.gov/pubmed/37198474 http://dx.doi.org/10.1038/s42255-023-00774-2 |
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