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Population plasma and urine pharmacokinetics and the probability of target attainment of fosfomycin in healthy male volunteers

PURPOSE: A population pharmacokinetic model of fosfomycin was developed in healthy volunteers after intravenous administration, and different dosing regimens were evaluated in terms of the probability of target attainment for Escherichia coli using both plasma and urinary pharmacokinetic/pharmacodyn...

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Detalles Bibliográficos
Autores principales: Edwina, Angela Elma, Koch, Birgit C. P., Muller, Anouk E., al Jalali, Valentin, Matzneller, Peter, Zeitlinger, Markus, Sassen, Sebastiaan D. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229474/
https://www.ncbi.nlm.nih.gov/pubmed/37060459
http://dx.doi.org/10.1007/s00228-023-03477-5