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Transcriptional analysis reveals that the intracellular lipid accumulation impairs gene expression profiles involved in insulin response-associated cardiac functionality

Cardiovascular disease (CVD) is a multisystemic and multicellular pathology that is generally associated with high levels of atherogenic lipoproteins in circulation. These lipoproteins tend to be retained and modified, for example, aggregated low-density lipoprotein (aggLDL), in the extracellular ma...

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Detalles Bibliográficos
Autores principales: Actis Dato, Virginia, Paz, María C., Rey, Federico E., Sánchez, María C., Llorente-Cortés, Vicenta, Chiabrando, Gustavo A., Ceschin, Danilo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229538/
https://www.ncbi.nlm.nih.gov/pubmed/37253991
http://dx.doi.org/10.1038/s41598-023-35951-6