Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity

The imbalance between pathogenic and protective T cell subsets is a cardinal feature of autoimmune disorders such as multiple sclerosis (MS). Emerging evidence indicates that endogenous and dietary-induced changes in fatty acid metabolism have a major impact on both T cell fate and autoimmunity. To...

Descripción completa

Detalles Bibliográficos
Autores principales: Grajchen, Elien, Loix, Melanie, Baeten, Paulien, Côrte-Real, Beatriz F., Hamad, Ibrahim, Vanherle, Sam, Haidar, Mansour, Dehairs, Jonas, Broos, Jelle Y., Ntambi, James M., Zimmermann, Robert, Breinbauer, Rolf, Stinissen, Piet, Hellings, Niels, Verberk, Sanne G. S., Kooij, Gijs, Giera, Martin, Swinnen, Johannes V., Broux, Bieke, Kleinewietfeld, Markus, Hendriks, Jerome J. A., Bogie, Jeroen F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229556/
https://www.ncbi.nlm.nih.gov/pubmed/37041314
http://dx.doi.org/10.1038/s41423-023-01011-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229556/
https://www.ncbi.nlm.nih.gov/pubmed/37041314
http://dx.doi.org/10.1038/s41423-023-01011-2

Ejemplares similares