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RANKL(+) senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics
In dentistry, orthodontic root resorption is a long-lasting issue with no effective treatment strategy, and its mechanisms, especially those related to senescent cells, remain largely unknown. Here, we used an orthodontic intrusion tooth movement model with an L-loop in rats to demonstrate that mech...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229558/ https://www.ncbi.nlm.nih.gov/pubmed/37253719 http://dx.doi.org/10.1038/s41368-023-00228-1 |