RANKL(+) senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics

In dentistry, orthodontic root resorption is a long-lasting issue with no effective treatment strategy, and its mechanisms, especially those related to senescent cells, remain largely unknown. Here, we used an orthodontic intrusion tooth movement model with an L-loop in rats to demonstrate that mech...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Nishiura, Aki, Morikuni, Hidetoshi, Deng, Wenqi, Tsujibayashi, Toru, Momota, Yoshihiro, Azetsu, Yuki, Takami, Masamichi, Honda, Yoshitomo, Matsumoto, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229558/
https://www.ncbi.nlm.nih.gov/pubmed/37253719
http://dx.doi.org/10.1038/s41368-023-00228-1

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