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TGF-β controls development of TCRγδ(+)CD8αα(+) intestinal intraepithelial lymphocytes

γδ intestinal intraepithelial lymphocytes (IELs) constitute the majority of IELs with unique CD8αα(+) homodimers that are distinct from γδT cells in other tissues. However, it remains largely unclear how those cells develop. Here we show that transforming growth factor beta (TGF-β) signaling control...

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Detalles Bibliográficos
Autores principales: Han, Jiajia, Liu, Na, Jin, Wenwen, Zanvit, Peter, Zhang, Dunfang, Xu, Junji, Bynum, Andrew, Kazmi, Rida, Zhang, Jianmin, He, Wei, Chen, WanJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229584/
https://www.ncbi.nlm.nih.gov/pubmed/37253786
http://dx.doi.org/10.1038/s41421-023-00542-2