Cargando…
TGF-β controls development of TCRγδ(+)CD8αα(+) intestinal intraepithelial lymphocytes
γδ intestinal intraepithelial lymphocytes (IELs) constitute the majority of IELs with unique CD8αα(+) homodimers that are distinct from γδT cells in other tissues. However, it remains largely unclear how those cells develop. Here we show that transforming growth factor beta (TGF-β) signaling control...
Autores principales: | Han, Jiajia, Liu, Na, Jin, Wenwen, Zanvit, Peter, Zhang, Dunfang, Xu, Junji, Bynum, Andrew, Kazmi, Rida, Zhang, Jianmin, He, Wei, Chen, WanJun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229584/ https://www.ncbi.nlm.nih.gov/pubmed/37253786 http://dx.doi.org/10.1038/s41421-023-00542-2 |
Ejemplares similares
-
Identification and Regulation of TCRαβ(+)CD8αα(+) Intraepithelial Lymphocytes in Murine Oral Mucosa
por: Wu, Ruiqing, et al.
Publicado: (2020) -
Development and function of natural TCR(+) CD8αα(+) intraepithelial lymphocytes
por: Gui, Yuanyuan, et al.
Publicado: (2022) -
Control of CD8αα intestinal intraepithelial lymphocyte development by TGF-β
por: Konkel, Joanne E., et al.
Publicado: (2011) -
Dominant Negative FADD/MORT1 Inhibits the Development of Intestinal Intraepithelial Lymphocytes With a Marked Defect on CD8αα+TCRγδ+ T Cells
por: Zhang, Xuerui, et al.
Publicado: (2018) -
Thymic progenitors of TCRαβ(+) CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development
por: Golec, Dominic P., et al.
Publicado: (2017)