Deep learning model accurately classifies metastatic tumors from primary tumors based on mutational signatures

Metastatic propagation is the leading cause of death for most cancers. Prediction and elucidation of metastatic process is crucial for the treatment of cancer. Even though somatic mutations have been linked to tumorigenesis and metastasis, it is less explored whether metastatic events can be identif...

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Detalles Bibliográficos
Autores principales: Zheng, Weisheng, Pu, Mengchen, Li, Xiaorong, Du, Zhaolan, Jin, Sutong, Li, Xingshuai, Zhou, Jielong, Zhang, Yingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229594/
https://www.ncbi.nlm.nih.gov/pubmed/37253775
http://dx.doi.org/10.1038/s41598-023-35842-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229594/
https://www.ncbi.nlm.nih.gov/pubmed/37253775
http://dx.doi.org/10.1038/s41598-023-35842-w

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