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Allosteric regulation of the 20S proteasome by the Catalytic Core Regulators (CCRs) family
Controlled degradation of proteins is necessary for ensuring their abundance and sustaining a healthy and accurately functioning proteome. One of the degradation routes involves the uncapped 20S proteasome, which cleaves proteins with a partially unfolded region, including those that are damaged or...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229617/ https://www.ncbi.nlm.nih.gov/pubmed/37253751 http://dx.doi.org/10.1038/s41467-023-38404-w |