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Allosteric regulation of the 20S proteasome by the Catalytic Core Regulators (CCRs) family

Controlled degradation of proteins is necessary for ensuring their abundance and sustaining a healthy and accurately functioning proteome. One of the degradation routes involves the uncapped 20S proteasome, which cleaves proteins with a partially unfolded region, including those that are damaged or...

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Detalles Bibliográficos
Autores principales: Deshmukh, Fanindra Kumar, Ben-Nissan, Gili, Olshina, Maya A., Füzesi-Levi, Maria G., Polkinghorn, Caley, Arkind, Galina, Leushkin, Yegor, Fainer, Irit, Fleishman, Sarel J., Tawfik, Dan, Sharon, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229617/
https://www.ncbi.nlm.nih.gov/pubmed/37253751
http://dx.doi.org/10.1038/s41467-023-38404-w