Antibody blockade of Jagged1 attenuates choroidal neovascularization

Antibody-based blocking of vascular endothelial growth factor (VEGF) reduces choroidal neovascularization (CNV) and retinal edema, rescuing vision in patients with neovascular age-related macular degeneration (nAMD). However, poor response and resistance to anti-VEGF treatment occurs. We report that...

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Detalles Bibliográficos
Autores principales: Gjølberg, Torleif Tollefsrud, Wik, Jonas Aakre, Johannessen, Hanna, Krüger, Stig, Bassi, Nicola, Christopoulos, Panagiotis F., Bern, Malin, Foss, Stian, Petrovski, Goran, Moe, Morten C., Haraldsen, Guttorm, Fosse, Johanna Hol, Skålhegg, Bjørn Steen, Andersen, Jan Terje, Sundlisæter, Eirik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229650/
https://www.ncbi.nlm.nih.gov/pubmed/37253747
http://dx.doi.org/10.1038/s41467-023-38563-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229650/
https://www.ncbi.nlm.nih.gov/pubmed/37253747
http://dx.doi.org/10.1038/s41467-023-38563-w

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