Diosmin nanocrystal gel alleviates imiquimod-induced psoriasis in rats via modulating TLR7,8/NF-κB/micro RNA-31, AKT/mTOR/P70S6K milieu, and Tregs/Th17 balance

ABSTRACT: Diosmin is a flavonoid with promising anti-inflammatory and antioxidant properties. However, it has difficult physicochemical characteristics since its solubility demands a pH level of 12, which has an impact on the drug’s bioavailability. The aim of this work is the development and charac...

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Detalles Bibliográficos
Autores principales: Shahine, Yasmine, El-Aal, Sarah A. Abd, Reda, Ahmed M., Sheta, Eman, Atia, Nouran M., Abdallah, Ossama Y., Ibrahim, Sherihan Salaheldin Abdelhamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229696/
https://www.ncbi.nlm.nih.gov/pubmed/37010718
http://dx.doi.org/10.1007/s10787-023-01198-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229696/
https://www.ncbi.nlm.nih.gov/pubmed/37010718
http://dx.doi.org/10.1007/s10787-023-01198-w

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