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Impact of Different Saccharides on the In-Process Stability of a Protein Drug During Evaporative Drying: From Sessile Droplet Drying to Lab-Scale Spray Drying

OBJECTIVES: Solid biopharmaceutical products can circumvent lower temperature storage and transport and increase remote access with lower carbon emissions and energy consumption. Saccharides are known stabilizers in a solid protein produced via lyophilization and spray drying (SD). Thus, it is essen...

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Detalles Bibliográficos
Autores principales: Dieplinger, Johanna, Pinto, Joana T., Dekner, Michael, Brachtl, Gerald, Paudel, Amrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229717/
https://www.ncbi.nlm.nih.gov/pubmed/37012535
http://dx.doi.org/10.1007/s11095-023-03498-w