Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7

Tumors create an immunosuppressive tumor microenvironment by altering protein expression, but also by changing their glycosylation status, like altered expression of sialoglycans. Sialoglycans are capped with sialic acid sugar residues and are recognized by Siglec immune receptors. Siglec-7 is an in...

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Detalles Bibliográficos
Autores principales: van Houtum, Eline J. H., Kers-Rebel, Esther D., Looman, Maaike W., Hooijberg, Erik, Büll, Christian, Granado, Daniel, Cornelissen, Lenneke A. M., Adema, Gosse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229725/
https://www.ncbi.nlm.nih.gov/pubmed/37253806
http://dx.doi.org/10.1007/s00018-023-04816-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229725/
https://www.ncbi.nlm.nih.gov/pubmed/37253806
http://dx.doi.org/10.1007/s00018-023-04816-6

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