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Therapeutic mechanism of baicalein in peritoneal dialysis-associated peritoneal fibrosis based on network pharmacology and experimental validation

Baicalein (5,6,7-trihydroxyflavone) is a traditional Chinese medicine with multiple pharmacological and biological activities including anti-inflammatory and anti-fibrotic effects. However, whether baicalein has a therapeutic impact on peritoneal fibrosis has not been reported yet. In the present st...

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Detalles Bibliográficos
Autores principales: Lu, Xiaohui, Wu, Kefei, Jiang, Simin, Li, Yi, Wang, Yating, Li, Hongyu, Li, Guanglan, Liu, Qinghua, Zhou, Yi, Chen, Wei, Mao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229821/
https://www.ncbi.nlm.nih.gov/pubmed/37266145
http://dx.doi.org/10.3389/fphar.2023.1153503