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Chronic corticosterone exposure disrupts hepatic and intestinal bile acid metabolism in chicken

OBJECTIVE: Chronic stress leads to a high circulating level of glucocorticoids, which disrupts lipid metabolism and causes non-alcoholic fatty liver disease in mice and humans. Meanwhile, bile acid (BA), a class of metabolites initially synthesized in the liver and further metabolized by gut microbi...

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Detalles Bibliográficos
Autores principales: Wu, Lei, Liu, Xinyi, Zhang, Aijia, Chen, Huimin, Zhao, Ruqian, Jia, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229839/
https://www.ncbi.nlm.nih.gov/pubmed/37266385
http://dx.doi.org/10.3389/fvets.2023.1147024