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Skin gluten-related disorders: new and old cutaneous manifestations to be considered
The term gluten-related disorders (GRD) refer to a spectrum of different clinical manifestations triggered by the ingestion of gluten in genetically susceptible individuals, including coeliac disease (CD), wheat allergy and non-celiac gluten sensitivity (NCGS). GRD are characterized by a large varie...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229844/ https://www.ncbi.nlm.nih.gov/pubmed/37265490 http://dx.doi.org/10.3389/fmed.2023.1155288 |
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author | Verdelli, Alice Corrà, Alberto Mariotti, Elena Biancamaria Aimo, Cristina Quintarelli, Lavinia Ruffo di Calabria, Valentina Donati, Marta Elettra Bonciolini, Veronica Antiga, Emiliano Caproni, Marzia |
author_facet | Verdelli, Alice Corrà, Alberto Mariotti, Elena Biancamaria Aimo, Cristina Quintarelli, Lavinia Ruffo di Calabria, Valentina Donati, Marta Elettra Bonciolini, Veronica Antiga, Emiliano Caproni, Marzia |
author_sort | Verdelli, Alice |
collection | PubMed |
description | The term gluten-related disorders (GRD) refer to a spectrum of different clinical manifestations triggered by the ingestion of gluten in genetically susceptible individuals, including coeliac disease (CD), wheat allergy and non-celiac gluten sensitivity (NCGS). GRD are characterized by a large variety of clinical presentations with both intestinal and extra-intestinal manifestations. The latter may affect almost every organ of the body, including the skin. Besides the well-known association between CD and dermatitis herpetiformis, considered as the cutaneous specific manifestation of CD, many other muco-cutaneous disorders have been associated to GRD. In this review, we analyzed the main features of dermatological diseases with a proven association with GRD and those that improve after a gluten-free diet, focusing on the newly described cutaneous manifestations associated with NCGS. Our main hypothesis is that a “cutaneous-gluten sensitivity,” as specific cutaneous manifestation of NCGS, may exist and could represent a diagnostic marker of NCGS. |
format | Online Article Text |
id | pubmed-10229844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102298442023-06-01 Skin gluten-related disorders: new and old cutaneous manifestations to be considered Verdelli, Alice Corrà, Alberto Mariotti, Elena Biancamaria Aimo, Cristina Quintarelli, Lavinia Ruffo di Calabria, Valentina Donati, Marta Elettra Bonciolini, Veronica Antiga, Emiliano Caproni, Marzia Front Med (Lausanne) Medicine The term gluten-related disorders (GRD) refer to a spectrum of different clinical manifestations triggered by the ingestion of gluten in genetically susceptible individuals, including coeliac disease (CD), wheat allergy and non-celiac gluten sensitivity (NCGS). GRD are characterized by a large variety of clinical presentations with both intestinal and extra-intestinal manifestations. The latter may affect almost every organ of the body, including the skin. Besides the well-known association between CD and dermatitis herpetiformis, considered as the cutaneous specific manifestation of CD, many other muco-cutaneous disorders have been associated to GRD. In this review, we analyzed the main features of dermatological diseases with a proven association with GRD and those that improve after a gluten-free diet, focusing on the newly described cutaneous manifestations associated with NCGS. Our main hypothesis is that a “cutaneous-gluten sensitivity,” as specific cutaneous manifestation of NCGS, may exist and could represent a diagnostic marker of NCGS. Frontiers Media S.A. 2023-05-17 /pmc/articles/PMC10229844/ /pubmed/37265490 http://dx.doi.org/10.3389/fmed.2023.1155288 Text en Copyright © 2023 Alice, Corrà, Mariotti, Aimo, Quintarelli, Ruffo di Calabria, Elettra Donati, Bonciolini, Antiga and Caproni. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Verdelli, Alice Corrà, Alberto Mariotti, Elena Biancamaria Aimo, Cristina Quintarelli, Lavinia Ruffo di Calabria, Valentina Donati, Marta Elettra Bonciolini, Veronica Antiga, Emiliano Caproni, Marzia Skin gluten-related disorders: new and old cutaneous manifestations to be considered |
title | Skin gluten-related disorders: new and old cutaneous manifestations to be considered |
title_full | Skin gluten-related disorders: new and old cutaneous manifestations to be considered |
title_fullStr | Skin gluten-related disorders: new and old cutaneous manifestations to be considered |
title_full_unstemmed | Skin gluten-related disorders: new and old cutaneous manifestations to be considered |
title_short | Skin gluten-related disorders: new and old cutaneous manifestations to be considered |
title_sort | skin gluten-related disorders: new and old cutaneous manifestations to be considered |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229844/ https://www.ncbi.nlm.nih.gov/pubmed/37265490 http://dx.doi.org/10.3389/fmed.2023.1155288 |
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