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Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus

The actin cytoskeleton plays a critical role in cancer cell invasion and metastasis; however, the coordination of its multiple functions remains unclear. Actin dynamics in the cytoplasm control the formation of invadopodia, which are membrane protrusions that facilitate cancer cell invasion by focus...

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Detalles Bibliográficos
Autores principales: Mgrditchian, Takouhie, Brown-Clay, Joshua, Hoffmann, Céline, Müller, Tanja, Filali, Liza, Ockfen, Elena, Mao, Xianqing, Moreau, Flora, Casellas, Carla Pou, Kaoma, Tony, Mittelbronn, Michel, Thomas, Clément
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229898/
https://www.ncbi.nlm.nih.gov/pubmed/37266453
http://dx.doi.org/10.3389/fcell.2023.1100938