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Interferon-β alleviates sepsis by SIRT1-mediated blockage of endothelial glycocalyx shedding

Sepsis is a life-threatening multi-organ dysfunction with high mortality caused by the body’s improper response to microbial infection. No new effective therapy has emerged that can adequately treat patients with sepsis. We previously demonstrated that interferon-β (IFN-β) protects against sepsis vi...

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Detalles Bibliográficos
Autores principales: Duan, Suhong, Kim, Seung-Gook, Lim, Hyung-Jin, Song, Hwa-Ryung, Han, Myung-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230016/
https://www.ncbi.nlm.nih.gov/pubmed/37013347
http://dx.doi.org/10.5483/BMBRep.2023-0030