Ubiquitin E3 ligases in cancer: somatic mutation and amplification

Defects in DNA double-strand break (DSB) repair signaling permit cancer cells to accumulate genomic alterations that confer their aggressive phenotype. Nevertheless, tumors depend on residual DNA repair abilities to survive the DNA damage induced by genotoxic stress. This is why only isolated DNA re...

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Detalles Bibliográficos
Autores principales: Jo, Eun-Hye, Kim, Mi-Yeon, Lee, Hyung-Ju, Park, Hee-Sae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Invited Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230019/
https://www.ncbi.nlm.nih.gov/pubmed/37081755
http://dx.doi.org/10.5483/BMBRep.2023-0037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230019/
https://www.ncbi.nlm.nih.gov/pubmed/37081755
http://dx.doi.org/10.5483/BMBRep.2023-0037

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