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AGE-RAGE axis culminates into multiple pathogenic processes: a central road to neurodegeneration
Advanced glycation end-products (AGEs; e.g., glyoxal, methylglyoxal or carboxymethyl-lysine) are heterogenous group of toxic compounds synthesized in the body through both exogenous and endogenous pathways. AGEs are known to covalently modify proteins bringing about loss of functional alteration in...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230046/ https://www.ncbi.nlm.nih.gov/pubmed/37266370 http://dx.doi.org/10.3389/fnmol.2023.1155175 |