DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling

Dendritic cell immunoreceptor (DCIR) is an inhibitory C-type lectin receptor that acts as a negative regulator in the immune system and bone metabolism. We previously revealed that DCIR deficiency enhanced osteoclastogenesis and antigen presentation of dendritic cells, and that asialo-biantennary N-...

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Detalles Bibliográficos
Autores principales: Kaifu, Tomonori, Maruhashi, Takumi, Chung, Soo-Hyun, Shimizu, Kenji, Nakamura, Akira, Iwakura, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230091/
https://www.ncbi.nlm.nih.gov/pubmed/37266426
http://dx.doi.org/10.3389/fimmu.2023.1159058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230091/
https://www.ncbi.nlm.nih.gov/pubmed/37266426
http://dx.doi.org/10.3389/fimmu.2023.1159058

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