Cargando…

DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling

Dendritic cell immunoreceptor (DCIR) is an inhibitory C-type lectin receptor that acts as a negative regulator in the immune system and bone metabolism. We previously revealed that DCIR deficiency enhanced osteoclastogenesis and antigen presentation of dendritic cells, and that asialo-biantennary N-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaifu, Tomonori, Maruhashi, Takumi, Chung, Soo-Hyun, Shimizu, Kenji, Nakamura, Akira, Iwakura, Yoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230091/ https://www.ncbi.nlm.nih.gov/pubmed/37266426 http://dx.doi.org/10.3389/fimmu.2023.1159058

Ejemplares similares

DCIR in the “osteo-immune” system
por: Maruhashi, Takumi, et al.
Publicado: (2015)

DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis
por: Kaifu, Tomonori, et al.
Publicado: (2021)

Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor
por: SENO, Akimasa, et al.
Publicado: (2014)

M-CSF Potently Augments RANKL-Induced Resorption Activation in Mature Human Osteoclasts
por: Hodge, Jason M., et al.
Publicado: (2011)

Suppressive effects of (-)-tubaic acid on RANKL-induced osteoclast differentiation and bone resorption
por: Lim, Soomin, et al.
Publicado: (2023)

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
por: McDonald, Michelle M., et al.
Publicado: (2021)

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
por: McDonald, Michelle M., et al.
Publicado: (2021)

Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption
por: Jang, Jin Sun, et al.
Publicado: (2019)

ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts
por: Liang, Xinyue, et al.
Publicado: (2021)

TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens
por: Yabe, Rikio, et al.
Publicado: (2021)

RO4929097 regulates RANKL-induced osteoclast formation and LPS-mediated bone resorption
por: Huang, Tao, et al.
Publicado: (2021)

Water extract of Uncaria sinensis suppresses RANKL-induced bone loss by attenuating osteoclast differentiation and bone resorption
por: Ha, Hyunil, et al.
Publicado: (2017)

Inhibitory Effects of Rhaponticin on Osteoclast Formation and Resorption by Targeting RANKL-Induced NFATc1 and ROS Activity
por: He, Jianbo, et al.
Publicado: (2021)

Retinoic Acid Increases Proliferation of Human Osteoclast Progenitors and Inhibits RANKL-Stimulated Osteoclast Differentiation by Suppressing RANK
por: Hu, Lijuan, et al.
Publicado: (2010)

Osteoclasts secrete osteopontin into resorption lacunae during bone resorption
por: Luukkonen, Jani, et al.
Publicado: (2019)

Effect on Osteoclast Differentiation and ER Stress Downregulation by Amygdalin and RANKL Binding Interaction
por: Trang, Nguyen Minh, et al.
Publicado: (2022)

Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1
por: Ibáñez, Lidia, et al.
Publicado: (2022)

ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption
por: Qiu, Heng, et al.
Publicado: (2023)

DCIR3 and DCIR4 are widely expressed among tissue-resident macrophages with the exception of microglia and alveolar macrophages
por: Okada, Ryo, et al.
Publicado: (2020)

Muramyl Dipeptide Enhances Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption through Increased RANKL Expression in Stromal Cells
por: Ishida, Masahiko, et al.
Publicado: (2015)

Piceatannol attenuates RANKL-induced osteoclast differentiation and bone resorption by suppressing MAPK, NF-κB and AKT signalling pathways and promotes Caspase3-mediated apoptosis of mature osteoclasts
por: Yan, Liuliu, et al.
Publicado: (2019)

α-Tocopheryl Succinate Inhibits Osteoclast Formation by Suppressing Receptor Activator of Nuclear Factor-kappaB Ligand (RANKL) Expression and Bone Resorption
por: Kim, Ha-Neui, et al.
Publicado: (2012)

Sitagliptin, An Anti-diabetic Drug, Suppresses Estrogen Deficiency-Induced OsteoporosisIn Vivo and Inhibits RANKL-Induced Osteoclast Formation and Bone Resorption In Vitro
por: Wang, Chuandong, et al.
Publicado: (2017)

Fangchinoline protects against bone loss in OVX mice via inhibiting osteoclast formation, bone resorption and RANKL-induced signaling
por: Zhou, Lin, et al.
Publicado: (2020)

Magnolol Inhibits Osteoclast Differentiation via Suppression of RANKL Expression
por: Hwang, Youn-Hwan, et al.
Publicado: (2018)

The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17
por: Makusheva, Yulia, et al.
Publicado: (2022)

Effect of caspases and RANKL induced by heavy force in orthodontic root resorption
por: Minato, Yukari, et al.
Publicado: (2018)

Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation
por: Tsubaki, Masanobu, et al.
Publicado: (2014)

Microcracks and Osteoclast Resorption Activity In Vitro
por: Rumpler, Monika, et al.
Publicado: (2012)

RANKL-Induced Btn2a2 – A T Cell Immunomodulatory Molecule – During Osteoclast Differentiation Fine-Tunes Bone Resorption
por: Frech, Michael, et al.
Publicado: (2021)

Structure and establishment of the German Cochlear Implant Registry (DCIR)
por: Stöver, T., et al.
Publicado: (2023)

Obatoclax Regulates the Proliferation and Fusion of Osteoclast Precursors through the Inhibition of ERK Activation by RANKL
por: Oh, Ju Hee, et al.
Publicado: (2015)

The effects of seeding density and osteoclastic supplement concentration on osteoclastic differentiation and resorption
por: Remmers, Stefan J.A., et al.
Publicado: (2022)

GPR120 Inhibits RANKL-Induced Osteoclast Formation and Resorption by Attenuating Reactive Oxygen Species Production in RAW264.7 Murine Macrophages
por: Sithole, Cynthia, et al.
Publicado: (2021)

Estrogen Inhibits Bone Resorption by Directly Inducing Apoptosis of the Bone-resorbing Osteoclasts
por: Kameda, Takashi, et al.
Publicado: (1997)

Effects of ibandronate-hydroxyapatite on resorptive activity of osteoclasts
por: Zhang, Xiaohui, et al.
Publicado: (2011)

Septins are critical regulators of osteoclastic bone resorption
por: Møller, Anaïs M. J., et al.
Publicado: (2018)

Rab GTPases in Osteoclastic Bone Resorption and Autophagy
por: Roy, Michèle, et al.
Publicado: (2020)

HIV-1 Induces DCIR Expression in CD4(+) T Cells
por: Lambert, Alexandra A., et al.
Publicado: (2010)

Is RANKL inhibition both anti-resorptive and anabolic in rheumatoid arthritis?
por: Sims, Natalie A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_333n3qv05ujo8pm1pdke2cki29