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Single-cell chromatin accessibility of developing murine pancreas identifies cell state-specific gene regulatory programs

Numerous studies have characterized the existence of cell subtypes, along with their corresponding transcriptional profiles, within the developing mouse pancreas. The upstream mechanisms that initiate and maintain gene expression programs across cell states, however, remain largely unknown. Here, we...

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Detalles Bibliográficos
Autores principales: de la O, Sean, Yao, Xinkai, Chang, Sean, Liu, Zhe, Sneddon, Julie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230264/
https://www.ncbi.nlm.nih.gov/pubmed/37178817
http://dx.doi.org/10.1016/j.molmet.2023.101735