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Isotoxic dose escalated radiotherapy for glioblastoma based on diffusion-weighted MRI and tumor control probability—an in-silico study

OBJECTIVES: Glioblastoma (GBM) is the most common malignant primary brain tumor with local recurrence after radiotherapy (RT), the most common mode of failure. Standard RT practice applies the prescription dose uniformly across tumor volume disregarding radiological tumor heterogeneity. We present a...

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Detalles Bibliográficos
Autores principales: Pang, Yaru, Kosmin, Michael, Li, Zhuangling, Deng, Xiaonian, Li, Zihuang, Li, Xianming, Zhang, Ying, Royle, Gary, Manolopoulos, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230387/
https://www.ncbi.nlm.nih.gov/pubmed/37102792
http://dx.doi.org/10.1259/bjr.20220384