Targeting glutaminase is therapeutically effective in ibrutinib-resistant mantle cell lymphoma

Mantle cell lymphoma (MCL) is an incurable B-cell non-Hodgkin lymphoma characterized by frequent relapses. The development of resistance to ibrutinib therapy remains a major challenge in MCL. We previously showed that glutaminolysis is associated with resistance to ibrutinib. In this study, we confi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Lingzhi, Nie, Lei, Jordan, Alexa, Cai, Qingsong, Liu, Yang, Li, Yijing, Che, Yuxuan, Vargas, Jovanny, Chen, Zhihong, Leeming, Angela, Wang, Wei, Yao, Yixin, Wang, Michael, Jiang, Vivian Changying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Non-Hodgkin Lymphoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230437/
https://www.ncbi.nlm.nih.gov/pubmed/36420799
http://dx.doi.org/10.3324/haematol.2022.281538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230437/
https://www.ncbi.nlm.nih.gov/pubmed/36420799
http://dx.doi.org/10.3324/haematol.2022.281538

Ejemplares similares