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Targeting glutaminase is therapeutically effective in ibrutinib-resistant mantle cell lymphoma
Mantle cell lymphoma (MCL) is an incurable B-cell non-Hodgkin lymphoma characterized by frequent relapses. The development of resistance to ibrutinib therapy remains a major challenge in MCL. We previously showed that glutaminolysis is associated with resistance to ibrutinib. In this study, we confi...
Autores principales: | Li, Lingzhi, Nie, Lei, Jordan, Alexa, Cai, Qingsong, Liu, Yang, Li, Yijing, Che, Yuxuan, Vargas, Jovanny, Chen, Zhihong, Leeming, Angela, Wang, Wei, Yao, Yixin, Wang, Michael, Jiang, Vivian Changying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230437/ https://www.ncbi.nlm.nih.gov/pubmed/36420799 http://dx.doi.org/10.3324/haematol.2022.281538 |
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