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Honokiol attenuates acetaminophen-induced acute liver injury by inhibiting hepatic CYP1A2 activity and improving liver mitochondrial dysfunction

OBJECTIVE: Acetaminophen (APAP) overdose is a common cause of liver injury. This study aimed to investigate the protective effect of honokiol (Hon) against APAP-induced hepatotoxicity and its potential mechanism. METHODS: C57BL/6 mice were administrated with Hon (10 and 30 mg/kg) after APAP (300 mg/...

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Detalles Bibliográficos
Autores principales:	Miao, Xiaolei, Jin, Chengting, Liu, Jiao, Wang, Junjun, Chen, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230637/ https://www.ncbi.nlm.nih.gov/pubmed/37265773 http://dx.doi.org/10.1016/j.chmed.2023.01.002

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