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Spatial analysis of stromal signatures identifies invasive front carcinoma-associated fibroblasts as suppressors of anti-tumor immune response in esophageal cancer

BACKGROUND: Increasing evidence indicates that the tumor microenvironment (TME) is a crucial determinant of cancer progression. However, the clinical and pathobiological significance of stromal signatures in the TME, as a complex dynamic entity, is still unclear in esophageal squamous cell carcinoma...

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Detalles Bibliográficos
Autores principales: He, Jian-Zhong, Chen, Yang, Zeng, Fa-Min, Huang, Qing-Feng, Zhang, Hai-Feng, Wang, Shao-Hong, Yu, Shuai-Xia, Pang, Xiao-Xiao, Liu, Ye, Xu, Xiu-E, Wu, Jian-Yi, Shen, Wen-Jun, Li, Zhan-Yu, Li, En-Min, Xu, Li-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230698/
https://www.ncbi.nlm.nih.gov/pubmed/37254126
http://dx.doi.org/10.1186/s13046-023-02697-y