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Spatial analysis of stromal signatures identifies invasive front carcinoma-associated fibroblasts as suppressors of anti-tumor immune response in esophageal cancer
BACKGROUND: Increasing evidence indicates that the tumor microenvironment (TME) is a crucial determinant of cancer progression. However, the clinical and pathobiological significance of stromal signatures in the TME, as a complex dynamic entity, is still unclear in esophageal squamous cell carcinoma...
Autores principales: | He, Jian-Zhong, Chen, Yang, Zeng, Fa-Min, Huang, Qing-Feng, Zhang, Hai-Feng, Wang, Shao-Hong, Yu, Shuai-Xia, Pang, Xiao-Xiao, Liu, Ye, Xu, Xiu-E, Wu, Jian-Yi, Shen, Wen-Jun, Li, Zhan-Yu, Li, En-Min, Xu, Li-Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230698/ https://www.ncbi.nlm.nih.gov/pubmed/37254126 http://dx.doi.org/10.1186/s13046-023-02697-y |
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