Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing

BACKGROUND: Single-cell RNA-seq has emerged as an innovative technology used to study complex tissues and characterize cell types, states, and lineages at a single-cell level. Classification of bulk tumors by their individual cellular constituents has also created new opportunities to generate singl...

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Detalles Bibliográficos
Autores principales: Truong, Danh D., Lamhamedi-Cherradi, Salah-Eddine, Porter, Robert W., Krishnan, Sandhya, Swaminathan, Jyothishmathi, Gibson, Amber, Lazar, Alexander J., Livingston, J. Andrew, Gopalakrishnan, Vidya, Gordon, Nancy, Daw, Najat C., Navin, Nicholas E., Gorlick, Richard, Ludwig, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230784/
https://www.ncbi.nlm.nih.gov/pubmed/37254069
http://dx.doi.org/10.1186/s12885-023-10977-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230784/
https://www.ncbi.nlm.nih.gov/pubmed/37254069
http://dx.doi.org/10.1186/s12885-023-10977-1

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