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The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development

BACKGROUND: Tumor-associated macrophages (TAMs) are a major component of the tumor microenvironment (TME) and exert an important role in tumor progression. Due to the heterogeneity and plasticity of TAMs, modulating the polarization states of TAMs is considered as a potential therapeutic strategy fo...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Wei, Sisi, Dai, Suli, Li, Xiaoya, Wang, Huixia, Zhang, Hongtao, Sun, Guogui, Shan, Baoen, Zhao, Lianmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230994/
https://www.ncbi.nlm.nih.gov/pubmed/37217247
http://dx.doi.org/10.1136/jitc-2022-006230