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Role of RNA Domain Structure and Orientation in the Coxsackievirus B3 Virulence Phenotype

Coxsackievirus B3 (CVB3) is an enterovirus that causes diseases such as pancreatitis and myocarditis in humans. Approximately 10% of the CVB3 RNA genome consists of a highly structured 5′ untranslated region (5′ UTR) that is organized into six domains and contains a type I internal ribosome entry si...

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Detalles Bibliográficos
Autores principales: Phillips, Lydia, Tapprich, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231185/
https://www.ncbi.nlm.nih.gov/pubmed/37074194
http://dx.doi.org/10.1128/jvi.00448-23