Engineering Oncolytic Coxsackievirus A21 with Small Transgenes and Enabling Cell-Mediated Virus Delivery by Integrating Viral cDNA into the Genome

Coxsackievirus A21 (CVA21) is a naturally occurring RNA virus that, in preclinical studies and clinical trials, has demonstrated promising potential in treating a range of malignancies. Other oncolytic viruses, such as adenovirus, vesicular stomatitis virus, herpesvirus, and vaccinia virus, all can...

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Detalles Bibliográficos
Autores principales: Sam, Miranda, Selman, Mohammed, Zhao, Weilong, Jung, Jiwon, Willingham, Aarron, Phan, Uyen, Starling, Gary C., Gao, Qinshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Gene Delivery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231226/
https://www.ncbi.nlm.nih.gov/pubmed/37070982
http://dx.doi.org/10.1128/jvi.00309-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231226/
https://www.ncbi.nlm.nih.gov/pubmed/37070982
http://dx.doi.org/10.1128/jvi.00309-23

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