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Characterization of Ebola Virus Mucosal Challenge Routes in Cynomolgus Macaques

Zaïre ebolavirus (EBOV) causes Ebola virus disease (EVD), a devastating viral hemorrhagic fever in humans. Nonhuman primate (NHP) models of EVD traditionally use intramuscular infection with higher case fatality rates and reduced mean time-to-death compared to contact transmission typical of human c...

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Detalles Bibliográficos
Autores principales: Johnson, Dylan M., Brasel, Trevor, Massey, Shane, Smith, Jeanon, Garron, Tania, Wallace, Shannon, Yu, Xiaoying, Beasley, David W., Comer, Jason E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231233/
https://www.ncbi.nlm.nih.gov/pubmed/36975793
http://dx.doi.org/10.1128/jvi.01888-22