Cargando…

Characterization of Ebola Virus Mucosal Challenge Routes in Cynomolgus Macaques

Zaïre ebolavirus (EBOV) causes Ebola virus disease (EVD), a devastating viral hemorrhagic fever in humans. Nonhuman primate (NHP) models of EVD traditionally use intramuscular infection with higher case fatality rates and reduced mean time-to-death compared to contact transmission typical of human c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johnson, Dylan M., Brasel, Trevor, Massey, Shane, Smith, Jeanon, Garron, Tania, Wallace, Shannon, Yu, Xiaoying, Beasley, David W., Comer, Jason E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231233/ https://www.ncbi.nlm.nih.gov/pubmed/36975793 http://dx.doi.org/10.1128/jvi.01888-22

Ejemplares similares

Pandemic 1918 Influenza Virus Does Not Cause Lethal Infection in Rhesus or Cynomolgus Macaques
por: Chan, Mable, et al.
Publicado: (2022)

Evaluation of molnupiravir (EIDD-2801) efficacy against SARS-CoV-2 in the rhesus macaque model
por: Johnson, Dylan M., et al.
Publicado: (2023)

Seminal Simian Immunodeficiency Virus in Chronically Infected Cynomolgus Macaques Is Dominated by Virus Originating from Multiple Genital Organs
por: Houzet, Laurent, et al.
Publicado: (2018)

Establishment of a Cynomolgus Macaque Model of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Direct Inoculation of Adult T-Cell Leukemia Patient-Derived Cell Lines for HTLV-1 Infection
por: Urano, Emiko, et al.
Publicado: (2022)

Mucosal Challenge Ferret Models of Ebola Virus Disease
por: Brasel, Trevor, et al.
Publicado: (2021)

Naturally Occurring Single Mutations in Ebola Virus Observably Impact Infectivity
por: Wong, Gary, et al.
Publicado: (2018)

Host immunity associated with spontaneous suppression of viremia in therapy-naïve young rhesus macaques following neonatal SHIV infection
por: Evangelous, Tyler D., et al.
Publicado: (2023)

NK Cells Accumulate in Infected Tissues and Contribute to Pathogenicity of Ebola Virus in Mice
por: Fausther-Bovendo, H., et al.
Publicado: (2019)

Chronic Morphine Administration Differentially Modulates Viral Reservoirs in a Simian Immunodeficiency Virus SIVmac251-Infected Rhesus Macaque Model
por: Acharya, Arpan, et al.
Publicado: (2021)

Dose-Dependent Response to Infection with Ebola Virus in the Ferret Model and Evidence of Viral Evolution in the Eye
por: Watson, Robert J., et al.
Publicado: (2021)

Rapid Loss of CD4 T Cells by Pyroptosis during Acute SIV Infection in Rhesus Macaques
por: He, Xuan, et al.
Publicado: (2022)

African-Lineage Zika Virus Replication Dynamics and Maternal-Fetal Interface Infection in Pregnant Rhesus Macaques
por: Crooks, Chelsea M., et al.
Publicado: (2021)

Avatar Mice Underscore the Role of the T Cell-Dendritic Cell Crosstalk in Ebola Virus Disease and Reveal Mechanisms of Protection in Survivors
por: Rottstegge, Monika, et al.
Publicado: (2022)

Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques
por: Lo, Ming, et al.
Publicado: (2019)

Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants
por: Bricker, Katherine M., et al.
Publicado: (2022)

HIV Infection and Persistence in Pulmonary Mucosal Double Negative T Cells In Vivo
por: Meziane, Oussama, et al.
Publicado: (2020)

Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques
por: Hsu, Denise C., et al.
Publicado: (2018)

Presence of Inflammatory Group I and III Innate Lymphoid Cells in the Colon of Simian Immunodeficiency Virus-Infected Rhesus Macaques
por: Cogswell, Andrew, et al.
Publicado: (2020)

Immune Responses and Viral Persistence in Simian/Human Immunodeficiency Virus SHIV.C.CH848-Infected Rhesus Macaques
por: Ziani, Widade, et al.
Publicado: (2021)

Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression
por: Garcia-Mesa, Yoelvis, et al.
Publicado: (2020)

CD8 Lymphocyte Depletion Enhances the Latency Reversal Activity of the SMAC Mimetic AZD5582 in ART-Suppressed Simian Immunodeficiency Virus-Infected Rhesus Macaques
por: Mavigner, Maud, et al.
Publicado: (2021)

Comparison of Experimental Middle East Respiratory Syndrome Coronavirus Infection Acquired by Three Individual Routes of Infection in the Common Marmoset
por: Nelson, Michelle, et al.
Publicado: (2022)

Varying Viral Replication and Disease Profiles of H2N2 Influenza in Ferrets Is Associated with Virus Isolate and Inoculation Route
por: van de Ven, Koen, et al.
Publicado: (2022)

Impact of Early ARV Initiation on Relative Proportions of Effector and Regulatory CD8 T Cell in Mesenteric Lymph Nodes and Peripheral Blood During Acute SIV Infection of Rhesus Macaques
por: Yero, Alexis, et al.
Publicado: (2022)

Deep Gene Sequence Cluster Analyses of Multi-Virus-Infected Mucosal Tissue Reveal Enhanced Transmission of Acute HIV-1
por: Klein, Katja, et al.
Publicado: (2021)

Combination of CD8β Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques
por: McBrien, Julia B., et al.
Publicado: (2020)

Pharmacological Modulation of the Wnt/β-Catenin Pathway Inhibits Proliferation and Promotes Differentiation of Long-Lived Memory CD4(+) T Cells in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques
por: Mavigner, M., et al.
Publicado: (2019)

Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4(+) T Cells
por: Obregon-Perko, Veronica, et al.
Publicado: (2020)

Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans
por: Christensen, Shannon R., et al.
Publicado: (2019)

Modified Vaccinia Virus Ankara Can Induce Optimal CD8(+) T Cell Responses to Directly Primed Antigens Depending on Vaccine Design
por: Wong, Yik Chun, et al.
Publicado: (2019)

Possible Cross-Reactivity of Feline and White-Tailed Deer Antibodies against the SARS-CoV-2 Receptor Binding Domain
por: Hancock, Trevor J., et al.
Publicado: (2022)

Delayed Disease in Cynomolgus Macaques Exposed to Ebola Virus by an Intranasal Route
por: Johnston, Sara C., et al.
Publicado: (2021)

Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA
por: Gaebler, Christian, et al.
Publicado: (2021)

Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1
por: Tay, Matthew Zirui, et al.
Publicado: (2019)

Identification of Common CD8(+) T Cell Epitopes from Lassa Fever Survivors in Nigeria and Sierra Leone
por: Sakabe, Saori, et al.
Publicado: (2020)

A Single Amino Acid Substitution in the Novel H7N9 Influenza A Virus NS1 Protein Increases CPSF30 Binding and Virulence
por: Ayllon, Juan, et al.
Publicado: (2014)

Impact of HLA Selection Pressure on HIV Fitness at a Population Level in Mexico and Barbados
por: Juarez-Molina, Claudia I., et al.
Publicado: (2014)

Virus and Host Factors Affecting the Clinical Outcome of Bluetongue Virus Infection
por: Caporale, Marco, et al.
Publicado: (2014)

Acute-Phase CD8 T Cell Responses That Select for Escape Variants Are Needed to Control Live Attenuated Simian Immunodeficiency Virus
por: Harris, Max, et al.
Publicado: (2013)

High Production Rates Sustain In Vivo Levels of PD-1(high) Simian Immunodeficiency Virus-Specific CD8 T Cells in the Face of Rapid Clearance
por: Petrovas, Constantinos, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3lliocms3hec206d85k5j9vd9j