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Combinational Deletions of MGF110-9L and MGF505-7R Genes from the African Swine Fever Virus Inhibit TBK1 Degradation by an Autophagy Activator PIK3C2B To Promote Type I Interferon Production

African swine fever (ASF), caused by the African swine fever virus (ASFV), is a transboundary infectious disease of domestic pigs and wild boars, resulting in significant swine production losses. Currently, no effective commercial ASF vaccines or therapeutic options are available. A previous study h...

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Detalles Bibliográficos
Autores principales: Zhu, Guoqiang, Ren, Jingjing, Li, Dan, Ru, Yi, Qin, Xiaodong, Feng, Tao, Tian, Hong, Lu, Bingzhou, Shi, Dongfang, Shi, Zhengwang, Yang, Wenping, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231249/
https://www.ncbi.nlm.nih.gov/pubmed/37162350
http://dx.doi.org/10.1128/jvi.00228-23