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The high mutation rate at the D614G hotspot-furin cleavage site region increases the priming efficiency of the Spike protein by furin protease: analysis of Indonesian SARS-CoV-2 G614 variants obtained during the early COVID-19 pandemic

D614G mutation plays a significant role in the transmissibility of SARS-CoV-2. Identification of other mutations related to D614G mutation within the Spike protein is pivotal as they might contribute to the pathogenicity of SARS-CoV-2. This study aims to analyze the mutation rate of furin cleavage s...

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Detalles Bibliográficos
Autores principales: Gazali, Faris Muhammad, Wijayanti, Nastiti, Hakim, Mohamad Saifudin, Supriyati, Endah, Arguni, Eggi, Daniwijaya, Marselinus Edwin Widyanto, Nuryastuti, Titik, Nuhamunada, Matin, Nabilla, Rahma, Haryana, Sofia Mubarika, Wibawa, Tri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231289/
https://www.ncbi.nlm.nih.gov/pubmed/37363361
http://dx.doi.org/10.1007/s13337-023-00827-w