Low energy nebulization preserves integrity of SARS-CoV-2 mRNA vaccines for respiratory delivery

Nebulization of mRNA therapeutics can be used to directly target the respiratory tract. A promising prospect is that mucosal administration of lipid nanoparticle (LNP)-based mRNA vaccines may lead to a more efficient protection against respiratory viruses. However, the nebulization process can ruptu...

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Detalles Bibliográficos
Autores principales: van Rijn, Cees J. M., Vlaming, Killian E., Bem, Reinout A., Dekker, Rob J., Poortinga, Albert, Breit, Timo, van Leeuwen, Selina, Ensink, Wim A., van Wijnbergen, Kelly, van Hamme, John L., Bonn, Daniel, Geijtenbeek, Teunis B. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231294/
https://www.ncbi.nlm.nih.gov/pubmed/37258559
http://dx.doi.org/10.1038/s41598-023-35872-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231294/
https://www.ncbi.nlm.nih.gov/pubmed/37258559
http://dx.doi.org/10.1038/s41598-023-35872-4

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