The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1

Site-selective conjugation chemistry has proven effective to synthesize homogenously ubiquitinated histones. Recently, a powerful strategy using 2-((2-chloroethyl) amino) ethane-1-thiol (CAET) as a bifunctional handle was developed to generate chemically stable ubiquitin chains without racemization...

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Detalles Bibliográficos
Autores principales: Li, Zichen, Tong, Zebin, Gong, Qingyue, Ai, Huasong, Peng, Shuai, Chen, Cong, Chu, Guo-Chao, Li, Jia-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231317/
https://www.ncbi.nlm.nih.gov/pubmed/37265717
http://dx.doi.org/10.1039/d3sc00332a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231317/
https://www.ncbi.nlm.nih.gov/pubmed/37265717
http://dx.doi.org/10.1039/d3sc00332a

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