Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

Interferons (IFNs) are cytokines with potent antineoplastic and antiviral properties. IFNα has significant clinical activity in the treatment of myeloproliferative neoplasms (MPN), but the precise mechanisms by which it acts are not well understood. Here, we demonstrate that chromatin assembly facto...

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Detalles Bibliográficos
Autores principales: Saleiro, Diana, Kosciuczuk, Ewa M., Fischietti, Mariafausta, Perez, Ricardo E., Yang, G. Sohae, Eckerdt, Frank, Beauchamp, Elspeth M., Hou, Ye, Wang, Qixuan, Weinberg, Rona Singer, Fish, Eleanor N., Yue, Feng, Hoffman, Ronald, Platanias, Leonidas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231401/
https://www.ncbi.nlm.nih.gov/pubmed/37377894
http://dx.doi.org/10.1158/2767-9764.CRC-23-0010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231401/
https://www.ncbi.nlm.nih.gov/pubmed/37377894
http://dx.doi.org/10.1158/2767-9764.CRC-23-0010

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