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Cytolytic CD8(+) T cells infiltrate germinal centers to limit ongoing HIV replication in spontaneous controller lymph nodes

Follicular CD8(+) T cells (fCD8) mediate surveillance in lymph node (LN) germinal centers against lymphotropic infections and cancers, but precise mechanisms by which these cells mediate immune control remain incompletely resolved. To address this, we investigated functionality, clonotypic compartme...

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Detalles Bibliográficos
Autores principales: Collins, David R., Hitschfel, Julia, Urbach, Jonathan M., Mylvaganam, Geetha H., Ly, Ngoc L., Arshad, Umar, Racenet, Zachary J., Yanez, Adrienne G., Diefenbach, Thomas J., Walker, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231436/
https://www.ncbi.nlm.nih.gov/pubmed/37205767
http://dx.doi.org/10.1126/sciimmunol.ade5872