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Unsupervised Deep Learning Can Identify Protein Functional Groups from Unaligned Sequences

Interpreting protein function from sequence data is a fundamental goal of bioinformatics. However, our current understanding of protein diversity is bottlenecked by the fact that most proteins have only been functionally validated in model organisms, limiting our understanding of how function varies...

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Detalles Bibliográficos
Autores principales: David, Kyle T, Halanych, Kenneth M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231473/
https://www.ncbi.nlm.nih.gov/pubmed/37217837
http://dx.doi.org/10.1093/gbe/evad084