Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology

The p38 alpha mitogen-activated protein kinase (p38α) is linked to both innate and adaptive immune responses and is under investigation as a target for drug development in the context of Alzheimer’s disease (AD) and other conditions with neuroinflammatory dysfunction. While preclinical data has show...

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Detalles Bibliográficos
Autores principales: Braun, David J., Frazier, Hilaree N., Davis, Verda A., Coleman, Meggie J., Rogers, Colin B., Van Eldik, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231773/
https://www.ncbi.nlm.nih.gov/pubmed/37256881
http://dx.doi.org/10.1371/journal.pone.0286495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231773/
https://www.ncbi.nlm.nih.gov/pubmed/37256881
http://dx.doi.org/10.1371/journal.pone.0286495

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