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Humoral immunogenicity of a Coronavirus Disease 2019 (COVID-19) DNA vaccine in rhesus macaques (Macaca mulatta) delivered using needle-free jet injection

A SARS-CoV-2 DNA vaccine targeting the spike protein and delivered by jet injection, nCOV-S(JET), previously shown to protect wild-type and immunosuppressed Syrian hamsters (Mesocricetus auratus), was evaluated via two needle-free delivery methods in rhesus macaques (Macaca mulatta). The methods inc...

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Detalles Bibliográficos
Autores principales: Jay, Alexandra, Kwilas, Steven A., Josleyn, Matthew, Ricks, Keersten, Hooper, Jay W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231776/
https://www.ncbi.nlm.nih.gov/pubmed/37256884
http://dx.doi.org/10.1371/journal.pone.0275082