Single-cell analysis of adult human heart across healthy and cardiovascular disease patients reveals the cellular landscape underlying SARS-CoV-2 invasion of myocardial tissue through ACE2

BACKGROUND: The distribution of ACE2 and accessory proteases (ANAD17 and CTSL) in cardiovascular tissue and the host cell receptor binding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are crucial to understanding the virus’s cell invasion, which may play a significant role in dete...

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Detalles Bibliográficos
Autores principales: Chen, Cong, Wang, Jie, Liu, Yong-Mei, Hu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231857/
https://www.ncbi.nlm.nih.gov/pubmed/37259108
http://dx.doi.org/10.1186/s12967-023-04224-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231857/
https://www.ncbi.nlm.nih.gov/pubmed/37259108
http://dx.doi.org/10.1186/s12967-023-04224-1

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