APOE expression and secretion are modulated by mitochondrial dysfunction

Mitochondria influence cellular function through both cell-autonomous and non-cell autonomous mechanisms, such as production of paracrine and endocrine factors. Here, we demonstrate that mitochondrial regulation of the secretome is more extensive than previously appreciated, as both genetic and phar...

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Detalles Bibliográficos
Autores principales: Wynne, Meghan E, Ogunbona, Oluwaseun, Lane, Alicia R, Gokhale, Avanti, Zlatic, Stephanie A, Xu, Chongchong, Wen, Zhexing, Duong, Duc M, Rayaprolu, Sruti, Ivanova, Anna, Ortlund, Eric A, Dammer, Eric B, Seyfried, Nicholas T, Roberts, Blaine R, Crocker, Amanda, Shanbhag, Vinit, Petris, Michael, Senoo, Nanami, Kandasamy, Selvaraju, Claypool, Steven Michael, Barrientos, Antoni, Wingo, Aliza, Wingo, Thomas S, Rangaraju, Srikant, Levey, Allan I, Werner, Erica, Faundez, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231934/
https://www.ncbi.nlm.nih.gov/pubmed/37171075
http://dx.doi.org/10.7554/eLife.85779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231934/
https://www.ncbi.nlm.nih.gov/pubmed/37171075
http://dx.doi.org/10.7554/eLife.85779

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