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Biological rhythms in COVID-19 vaccine effectiveness in an observational cohort study of 1.5 million patients

BACKGROUND: Circadian rhythms are evident in basic immune processes, but it is unclear if rhythms exist in clinical endpoints like vaccine protection. Here, we examined associations between COVID-19 vaccination timing and effectiveness. METHODS: We retrospectively analyzed a large Israeli cohort wit...

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Detalles Bibliográficos
Autores principales: Hazan, Guy, Duek, Or A., Alapi, Hillel, Mok, Huram, Ganninger, Alex, Ostendorf, Elaine, Gierasch, Carrie, Chodick, Gabriel, Greenberg, David, Haspel, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231992/
https://www.ncbi.nlm.nih.gov/pubmed/37053011
http://dx.doi.org/10.1172/JCI167339