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TMEM16E regulates endothelial cell procoagulant activity and thrombosis

Endothelial cells (ECs) normally form an anticoagulant surface under physiological conditions, but switch to support coagulation following pathogenic stimuli. This switch promotes thrombotic cardiovascular disease. To generate thrombin at physiologic rates, coagulation proteins assemble on a membran...

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Detalles Bibliográficos
Autores principales: Schmaier, Alec A., Anderson, Papa F., Chen, Siyu M., El-Darzi, Emale, Aivasovsky, Ivan, Kaushik, Milan P., Sack, Kelsey D., Hartzell, H. Criss, Parikh, Samir M., Flaumenhaft, Robert, Schulman, Sol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231993/
https://www.ncbi.nlm.nih.gov/pubmed/36951953
http://dx.doi.org/10.1172/JCI163808