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TMEM16E regulates endothelial cell procoagulant activity and thrombosis
Endothelial cells (ECs) normally form an anticoagulant surface under physiological conditions, but switch to support coagulation following pathogenic stimuli. This switch promotes thrombotic cardiovascular disease. To generate thrombin at physiologic rates, coagulation proteins assemble on a membran...
Autores principales: | Schmaier, Alec A., Anderson, Papa F., Chen, Siyu M., El-Darzi, Emale, Aivasovsky, Ivan, Kaushik, Milan P., Sack, Kelsey D., Hartzell, H. Criss, Parikh, Samir M., Flaumenhaft, Robert, Schulman, Sol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231993/ https://www.ncbi.nlm.nih.gov/pubmed/36951953 http://dx.doi.org/10.1172/JCI163808 |
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